The hairpin labeling and tethering kit provides a highly efficient system to characterize DNA/RNA structures using high-resolution single-molecule optical tweezers. Short handles will result in a higher force resolution, while long handles are better suitable for experimental workflows involving fluorescence.
The labeling procedure relies on a DNA/RNA hairpin ligation to the functionalized DNA handles. The hairpin of interest (provided by the user) requires a flanking 15 nt DNA sequence both at the 5’ end and the 3’ end.
The kit contains a control hairpin containing the flanking 15 nt DNA sequences that can be used as quality control for the labeling and tethering procedures.
Our hairpin labeling and tethering kit relieves you from costs and time that are typically required for personnel training, troubleshooting, experiment optimization, and custom application development.
The kit enables 10 hairpin labelings
Estimated 1-3 weeks delivery time