STED Application Note Now Online

Today’s quantitative analysis of DNA-protein interactions at the single-molecule level requires the capability of measuring under biologically relevant conditions with high temporal resolution. This problem can especially be observed when in vitro experiments are linked with the in vivo situation … Continue Reading

C-Trap™ Installation at University of Groningen

LUMICKS is proud to announce that we successfully installed a C-Trap™ at the University of Groningen in the lab of professor Roos. The Roos group will use the optical tweezers-fluorescence microscopy system to investigate the structure and mechanics of viral … Continue Reading

LUMICKS Featured in De Ingenieur

LUMICKS has been featured in the Dutch magazine De Ingenieur with an article named “Bewegend DNA-beeld”, or a moving DNA-image. De Ingenieur is a monthly Dutch magazine that specializes in technological developments and the policies surrounding them. This month’s edition … Continue Reading

Interactions between Single Fibrin Fibers are Measured for the First Time

Cells and tissue change their structural properties to cope with large strains e.g. caused by blood flow and external stress. Understanding microstructural remodeling of the extracellular matrix requires knowledge of biological events down to the smallest scale. One of the … Continue Reading

Paper Using LUMICKS Technology Published in Nature

Great news: Another paper using LUMICKS technology was published, this time in Nature! Congratulations to the authors. Several are now part of LUMICKS. In the study “Sliding sleeves of XRCC4-XLF bridge DNA and connect fragments of broken DNA” Brouwer et al. … Continue Reading

Study using CTFM Published in Nature Communications

A new paper using the correlative optical tweezers-fluorescence microscopy (CTFM) technology has recently been published in Nature Communications. King, Peterman & Wuite show in “Unravelling the structural plasticity of stretched DNA under torsional constraint” that in torsionally constraint DNA concomitant … Continue Reading

Two More C-Trap™ Systems are Ready for Shipment

Last week the assembly of two new C-Trap™ systems was finished. We are really excited about the experiments the new users will be performing on the correlative optical tweezers and fluorescence microscopy system. Don’t want to miss out on LUMICKS’ … Continue Reading

CTFM Workshop at BIOCEV a Great Success

The latest workshop on correlative optical tweezers and fluorescence microscopy (CTFM) was a great success. On June 8 and 9 the participants joined the hands-on workshop and were updated on the latest developments on CTFM at BIOCEV in Prague. Interested … Continue Reading

LUMICKS Delivers C-Trap™ to BIOCEV Prague

In January 2016 LUMICKS installed a C-Trap™ Correlative Optical Tweezers Fluorescence microscope at the BIOCEV Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University in Vestec. Acquired by the research group of Dr. Zdeněk Lánský, the C-Trap™ … Continue Reading

First C-Trap™ Customer Installation

LUMICKS completed its first customer installation of a C-Trap™ instrument at the Georg August University in Göttingen. There the system will be used for studies on intermediate filaments.

CTFM Appears in Bionews

LUMICKS’ technology was featured in the Dutch journal Bionews, with articles on how the C-Trap™’s Correlative Tweezers-Fluorenscence Technology revealed that the working of the RAD51 protein in the DNA repair process takes place independent of BRCA2 proteins. This contrary to … Continue Reading

CTFM Results on RAD51 Appear in PNAS

In a recent publication, Correlative Tweezers-Fluorescence Microscopy was used to reveal a fundamental step in one of the most crucial biological process that occur in a cell: DNA repair. The article appeared in the renowned journal PNAS, and was portrayed … Continue Reading

VU Group Receives ERC Proof of Concept Grant

The group of Prof. Gijs Wuite and Prof. Erwin Peterman at the VU University Amsterdam received an ERC Proof of Concept grant to do a market study and product feasibility study for the recently developed single-molecule experimentation instrument of optical … Continue Reading